Some people may experience side effects when following the total diet replacement (TDR) plan. This is because TDR is a more intensive approach than most other food-based weight loss diets, involving rapid weight loss and changes to medications or usual food intake.

Not everyone will experience side effects, but the most common ones include:

  • Sensitivity to cold
  • Headache
  • Dizziness
  • Fatigue

These effects can usually be prevented or managed by following the TDR plan carefully, spacing TDR products at regular intervals, and drinking enough fluids throughout the day.